Stuart Campbell, 36, has not been seen since he left the Co-op store on Bridge Road in the Colinton area of Edinburgh at around 6.45pm on Tuesday March 22.
Despite carrying out extensive searches police have found no trace of him.
Mr Campbell’s mother Jane urged anyone with information to contact police.
She said: “I know everything that could have been done has been done, but I am not giving up on finding him.
“I would urge anyone with information about his disappearance to come forward to assist the police investigation.”
Chief Inspector Mark Hamilton, Area Commander for South West Edinburgh, urged anyone who can help the investigation to get in touch.
He said: “We are continuing to appeal for information six months on from Stuart’s disappearance as it is extremely frustrating for us all not knowing what has happened to him.
“Our investigations continue and we have carried out extensive searches led by the information we have had available to us. I want to reassure Stuart’s family and friends that a missing person inquiry is never closed and pleased be assured we will act of any new information that comes to light regarding his disappearance.
“Stuart is described as being 5ft 10in tall, with short brown hair. He was last seen wearing a dark-coloured jacket, green hooded top with white ties and grey jogging bottoms.”